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A CoLaz clinician in branded uniform talks a patient through anti-wrinkle aftercare at a calm, softly lit consultation desk

Injectables · 5 May 2026 · 7 min read

Anti-Wrinkle Treatment Aftercare: 10 Essential Tips

Alaiyka Parvez

By Alaiyka Parvez

Owner, CoLaz Aesthetics Clinic

The short version

  • Stay upright for four to six hours and keep pressure off the treated area so the product settles where it was placed.
  • Avoid heat, saunas, alcohol and strenuous exercise for the first twenty-four hours, and gentle facials or peels for about a week.
  • Mild redness, small bruises or tenderness at the injection points are normal and usually settle within a few days.
  • Muscles begin to relax from around day three, with the final result at about two weeks.
  • Any aftercare only works if the treatment was done well in the first place, so choose a qualified, regulated clinician.

Fresh from your anti-wrinkle treatment, it is normal to wonder what happens next. The appointment itself is quick, but what you do in the hours and days afterwards plays a real part in your final result. Small, simple actions help the product settle where the clinician placed it, so lines soften evenly and the effect lasts as long as it should.

Anti-wrinkle aftercare is the short list of things you do, and avoid, while the treatment settles. It means keeping pressure off the treated muscles, staying away from heat and hard exercise for a day, and giving your skin a gentle week. Done properly, good aftercare lowers the risk of side effects and helps the result look smooth. Here is the full guide.

What should you do in the first 24 hours?

The first few hours matter most, because this is when botulinum toxin begins to settle into the muscles it was injected into. Keeping things still and simple stops it drifting to muscles you did not want treated.

  • Stay upright for four to six hours. Staying upright after treatment helps keep the product in the targeted area rather than spreading to nearby muscles. No lying flat or bending over for long stretches.
  • Do not touch, rub or massage the area. Pressing on the treated area can move the product before it has settled. Leave your face alone, and skip the make-up brushes for the rest of the day.
  • Gently exercise the treated muscles. A little natural frowning or raising of the brows in the first hour is fine, and some clinicians suggest it, but there is no need to force it.
  • Skip the gym. The American Academy of Dermatology advises waiting before strenuous activity, because raised blood flow and repeated straining can affect how the product settles.

A CoLaz clinician reviews the treated areas with a patient after anti-wrinkle injections, both calm in a bright, clinical treatment room

What should you avoid for the first few days?

For two to three days, avoid anything that raises heat or blood flow to your face: saunas, steam rooms, sunbeds, hot yoga, very hot baths and heavy workouts. Heat and hard exercise can increase bruising and swelling and are best left until the area has settled.

It is also sensible to go easy on alcohol for the first day or two, since it thins the blood slightly and can make small bruises more likely. If you take regular blood-thinning medication, keep taking it as prescribed and simply mention it to your clinician before treatment rather than stopping anything yourself.

For your skincare, keep the first week gentle. Facials, chemical peels and exfoliating treatments can irritate the injection points while everything is settling, so leave them for about seven days. Plain cleansing, a simple moisturiser and daily SPF are all your skin needs in this window.

Which side effects are normal, and which are not?

Most side effects are mild, short-lived and caused by the needle rather than the product itself. The research on cosmetic botulinum toxin is reassuring: used in small, controlled doses by a trained injector, it has one of the most studied safety records in aesthetic medicine.

What is normal in the first few days:

  • Small pinpoint redness or raised bumps at the injection sites, usually gone within an hour or two.
  • Minor bruising, which a narrative review of aesthetic injectables lists among the common, self-limiting effects. It typically fades within a week and covers easily once the area can be touched again.
  • A mild headache or a slight feeling of tightness as the muscles begin to relax.

What is worth a call to your clinician: a drooping eyelid or brow, noticeable asymmetry, or any spreading weakness. These are uncommon, tend to be linked to injection technique and dosing rather than the product, and are one of the clearest reasons to choose an experienced injector. Trouble breathing or swallowing is very rare with cosmetic doses, but if it ever happened you should seek urgent medical advice straight away.

How should you sleep after treatment?

On the first night, sleep on your back if you can, and avoid pressing the treated side of your face into the pillow for the first few hours after treatment. It is a small thing, but it keeps pressure off the area while the product is still settling. After the first night you can return to your usual sleeping position.

When will you see the result?

Anti-wrinkle injections do not work instantly. You will usually notice the muscles start to soften from around day three, with the fuller effect building over the following week and the final result at about two weeks.

Because of that timeline, it is worth being patient before you judge the outcome. If a line still looks a little strong at day five, that is normal. Most clinics, CoLaz included, offer a review at around the two-week mark, which is the right time to check the result and add a small top-up if any area needs it. Booking anything sooner rarely tells you much, because the product is still working.

The effect is temporary. A literature review of botulinum toxin for facial lines describes results lasting roughly three to four months for most people, after which the muscle activity gradually returns and you can choose whether to repeat. Regular, well-spaced treatments over time can mean the muscle learns to relax, so some long-term patients find they need slightly less.

Close-up of smooth, evenly relaxed forehead skin after anti-wrinkle injections, photographed in soft natural light

How do you make the result last?

The single biggest factor in how well your result settles and lasts is not a cream or a trick, it is who did the treatment. Aftercare protects a good outcome; it cannot rescue a poorly placed one.

In the UK, anyone offering these injections should be working to recognised standards. Checking your practitioner on the Joint Council for Cosmetic Practitioners register, or on the government-backed Save Face register, is the simplest way to confirm you are in qualified hands. The product is a prescription-only medicine, so it must be prescribed and administered by, or under the supervision of, a suitably qualified professional.

Beyond that, the sensible long-term habits are the same ones that keep any skin looking its best: daily SPF, good hydration, not smoking, and treating lines early rather than waiting for them to set. At CoLaz, every anti-wrinkle plan starts with a free consultation where a qualified clinician assesses your face, talks through what is realistic, and writes the plan down before anything is booked. If injections are not the right route for your concern, we will say so and talk through alternatives such as dermal fillers or skin treatments instead.

The short version

Keep the first day calm: stay upright, hands off, no heat and no gym. Keep the first week gentle on your skin, expect a little redness or bruising, and give the result two weeks before you judge it. Then, when you are ready to repeat, book with a qualified, regulated clinician, because that decision matters more than any aftercare step.

You can read the full treatment detail on our anti-wrinkle injections page, or message your nearest clinic on WhatsApp for a straight answer to a specific question.

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About the author

Alaiyka Parvez

Alaiyka Parvez

Owner, CoLaz Aesthetics Clinic

Alaiyka Parvez bought the CoLaz franchise network in 2023, having joined the company as a Slough clinic employee in 2013 and gone on to open the Hounslow and Wembley franchises. She writes here on the treatments CoLaz delivers across its seven UK clinics.

Read more about Alaiyka and CoLaz →

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